Polycystic ovary syndrome (PCOS) is the most common cause of ovulatory disorders and female infertility. Signs and symptoms of PCOS may include anovulation or menstrual irregularities; ovarian cysts on ultrasound; hyperandrogenism including hirsutism, acne, and alopecia; insulin resistance; and obesity. Insulin resistance and secondary hyperinsulinemia appear to play a causative role in the development of PCOS. In addition, PCOS patients suffer from elevated oxidative stress and systemic inflammation. myo‑Inositol has been suggested as a first-line therapy in the management of PCOS, and has been shown to be effective in mitigating the symptoms of this syndrome and its associated comorbidities.