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SKU: BC:9288 Category:



  • Naturally sourced from the seed of African plant Griffonia simplicifolia
  • Unlike L-tryptophan, 5-HTP readily crosses the blood-brain barrier increasing central nervous system synthesis of serotonin11
  • Enteric coated to reduce the likelihood of nausea

Feature Summary

5-Hydroxytryptophan (5-HTP) is an amino acid that is the middle step between tryptophan and neurotransmitter serotonin. Scientific evidence indicates that low serotonin levels are linked to a number of common conditions, including depression, obesity, headache/migraine and fibromyalgia. 5-HTP boosts serotonin levels and may offer a benefit in conditions linked to low serotonin levels.1

5-HTP may help patients unresponsive to standard antidepressant drugs and some evidence suggests it may be comparable, if not superior, to conventional antidepressants, with fewer side effects.2 Taking 5-HTP can also aid pain syndromes such as migraine and fibromyalgia.3 It is thought both conditions reflect a serotonergic defect. Fibromyalgia suffers have experienced improved symptoms including pain severity, morning stiffness, and sleeplessness with 5-HTP supplementation.3,4,5 5-HTP is known to increase sleep quality, which is critical in those patients suffering from depression or fibromyalgia. In fact, 5-HTP is known to promote and maintain sleep in normal subjects, as well as those experiencing insomnia.6

Research has indicated that 5-HTP may aid weight loss. Early animal studies indicated that genetically obese rats had decreased activity of the enzyme that converts tryptophan to 5-HTP and subsequently serotonin, allowing them to over eat.7 The same mechanism exists in genetically predisposed humans. By providing preformed 5-HTP, this genetic defect is bypassed and more serotonin is manufactured. Human clinical trials have corroborated that 5-HTP is able to reduce caloric intake, promote satiety and induce weight loss without conscious effort by subjects to lose weight.8,9,10


Medicinal Ingredients

Each Caplet Contains:
L-5-Hydroxytryptophan (Griffonia simplicifolia) (seed) 100 mg

Non-Medicinal Ingredients

Dibasic calcium phosphate dihydrate, purified water, microcrystalline cellulose, enteric coating (purified water, ethylcellulose, medium chain triglycerides, oleic acid, carbohydrate gum [cellulose], glycerin, sodium alginate, stearic acid), vegetable grade magnesium stearate (lubricant).


Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten,yeast, soy, corn, egg, fish, shellfish, animal products,salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.

Recommended Adult Dose: 
Healthy Mood Balance: 1 caplet 3 times per day with food or as directed by a health care practitioner. To minimize the risk of gastrointestinal side effects, slowly increase up to the full dose over a period of 2 weeks. Use for a minimum of 1 week to see beneficial effects. Consult a health care practitioner for use beyond 1 year. 
Sleep Aid: 1 caplet 1–2 times per day with food, 30–45 minutes prior to bedtime, or as directed by a health care practitioner.


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