Glycine or Collagen?

by | | Gut Brain Axis

Glycine is the Amino Acid that Gives

Without knowing it, glycine is helping your body every day with muscle repair, cognitive function, metabolic health, and immunity. This amino acid assists in breaking down glycogen, fat and other nutrients to be used as energy at the cellular level.  When it comes to aging gracefully it plays a role with the important antioxidant glutathione as well as the human growth hormone.

In the brain glycine acts as neurotransmitter in a similar way to GABA. It is in fact released with GABA to calm or inhibit parts of the central nervous system.  Glycine modulates excitatory neurotransmissions as well, meaning that it can go both ways. This unique neurotransmitter helps with sleep, memory, mental performance, stress, anxiety and even severe mental illness. As a preventative measure for everything from fatigue to stroke this is a powerful supplement.

For stabilizing blood sugar research shows a significant benefit with 5 grams of glycine before each meal so 15 grams per day.  This amount would be difficult to get in either bone broth or collagen.  You’d need two full servings of collagen to get 5 grams of glycine.  With metabolic issues sky rocketing glycine can be an excellent therapeutic aid.

Anyone who over methylates can benefit from glycine because it buffers excess methyl groups.  Methylation is a biochemical process that has an impact on B vitamin status.  Without adequate B vitamins, the body generates less glycine.  Low B6 particularly can result in high oxalate production instead.  This causes a different kind of pain in the joints and can lead to kidney stones.

By restoring gut health you also support immunity.  This is one of the far reaching benefits of glycine.  Given that digestive disorders and autoimmune conditions have reached epidemic proportions it’s worth ensuring you are getting enough glycine.

Where to Get Your Glycine

I mentioned above a few reasons to take glycine in its free form and how it can be difficult to get a therapeutic dose otherwise.  Collagen loading is one way to bring up the balance in the body.  This means taking high doses for a few weeks.

One of the reasons bone broth has finally received so much attention is due to this amino acid along with proline and arginine. However its difficult to know what dose you are getting when you make bone broth yourself.  If you purchase both broth and the label tells how much protein there is per serving then the amount of glycine is a 3:10 ration.  So you get 3 grams of glycine per 10 grams of protein.

Both collagen and bone broth can be taken for maintenance.  Testing B vitamins, metabolism and neurotransmitters through organic acids testing will let you know what is needed.

Types of Collagen: How to choose?  

Grass-fed, bovine sources of collagen provide both type 1 and 3.  What this means is that it targets muscle growth as well as the joints, skin, hair and nails.  This is because Type 3 has proline which supports creatine production.

The parts of the animal that are often wasted are used to make collagen. Grass-fed, pasture raised animals supports a healthy ecosystem in ways that industrial agriculture can’t.  The benefits to humans consuming small amounts of ethically raised animal products is well known.  This is especially key for those with compromised digestive health or autoimmunity.  For recovery from injury, surgery or to alleviate the damaging side effects of some medications it can be considered medicine.  Women who are pregnant, breastfeeding and caring for small children benefit as well.

Collagen harvested from fish can also be very nourishing and done ethically.  However marine collagen has a higher price point.  If its not then likely this is because the source is farmed fish.  The bioavailability will therefore be compromised as the molecules are larger and therefore less absorbable.  Well sourced marine collagen contains only Type 1 collagen which is the most bioavailable and often marketed for beauty reasons.

Type 2 collagen from chicken sources is especially rich in cartilage.  For anyone taking MSM and glucosamine this may be a replacement especially if you try a higher dose.

Optimal Health & Hormones

I mentioned the human growth hormone (HGH).  By building up and breaking down muscle we actually stimulate a cascade of positive physiological responses in the body that keep us feeling and looking great.  I like to think of collagen and glycine as supporting an active lifestyle and optimal health.  The liver loves glycine and the liver is what helps balance other hormones.

Here are all the ways that glycine supports your to feel your best:

Energizes:  whether you suffer from chronic fatigue or are an athlete this nutrient improves energy

Metabolism:  balancing blood sugar is key to metabolic health and weight maintenance

Muscle growth: for those who have lost muscle mass from illness or are enjoying the benefits of strength training

Sleep and Nerves: glycine has a positive, regulating effect on the central nervous system

Digestion: helps repair the gut by helping form the two key elements required for this which are gelatin and collagen

Aging: as a powerful antioxidant it prevents cellular damage and can slow the various ways that aging shows up

Immunity: by improving gut health we improve immunity

Injury repair:  this includes post-birth or surgery, joint or ligament injuries and harmful side-effects of medications

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